Membrane Type (PTFE, GHP, PVDF, Nylon) — Typically, the first step in selecting a suitable filter is to choose a membrane that is chemically compatible with the sample (see chart opposite). For aqueous samples, it is preferable to use a hydrophilic membrane (GHP, PVDF or Nylon) versus a hydrophobic membrane (PTFE).
Sep 03, 2013 · GHP hydrophilic polypropylene (GH Polypro) is ideal for chemical compatibility, fast flow rates, low protein binding, and low levels of UV-absorbing extractables. Glass fiber prefilters allow for quick and easy filtration for difficult-to-filter aqueous solutions. PVDF membranes have excellent compatibility with aggressive acids and alcohols.
2. Consider Chemical Compatibility Chemical compatibility is defined as the ability of a filter material to resist select chemicals so that the pore structure is not adversely affected by chemical exposure, and the filter material does not shed particles or fibers to add extractables.
Millex® syringe filters are available in sterile and nonsterile formats, offered in many membrane and housing options to enable compatibility with multiple solvents and sample types for applications including HPLC, UHPLC, and dissolution testing.
The GHP membrane used in Pall Laboratory Acrodisc® syringe filters, centrifugal devices and Acroprep™ filter plates will be discontinued due to the rationalization of a key material from our supplier. However we are excited to announce the launch of the NEW wwPTFE universal membrane as a direct replacement for GHP filtration products.
The primary concern when choosing a solvent filter is solvent compatibility with the filter material. We offer several filters to accommodate the various types of HPLC solvents. Our GHP (hydrophilic polypropylene) membrane is a universal solvent membrane to reduce confusion with filter selection.
The Pall GH Polypro (GHP) hydrophilic polypropylene membrane offers maximum chemical compatibility. Pall GHP membrane offers low protein binding (96.5% recovery), and low extractables. Pall GHP Nanosep Centrifuge Devices can be spun at 14,000g with leak-free operation.
Aug 07, 2018 · To compare between all the common membranes and solvents, review the chemical compatibility chart in our guide to laboratory membrane filtration principles and chemical compatibility. You might also find it useful to follow our quick reference chart (below) or try our filter selector tool to find your membrane filter fast.
GH Polypro (GHP) Membrane Disc Filters. All purpose, universal membrane with maximum chemical compatibility for both aqueous solutions and aggressive solvents. Specifications. Filter Media Hydrophilic polypropylene Pore Size 0.2 and 0.45 µm Typical Thickness 0.2 µm: 101 µm (4.0 mils) 0.45 µm: 114 µm (4.5 mils) Typical Water Flow Rate mL/min/cm2at 0.7 bar (70 kPa, 10 psi) 0.2 µm: 20 0.45 µm: 31 Maximum Operating Temperature 55 °C (131 °F) Minimum Bubble Point - Water 0.2 µm: 2.9 bar
Membrane Choices GHP acrodiscs Solvent compatibility chart. ACRoDISC 13 mm 0.2 μm 0.45 μm Pack Size 100 300 1000 100 300 1000 Sample Membrane
Oct 29, 2021 · solvent compatibility 0.22 um syringe filter Acrodisc Acrodisc, Minispike Syringe Filter, GHP, 13 mm, 0.2 µm GHP has the broadest chemical compatibility and exhibits minimal protein binding. WAT097962 Acrodisc, Minispike Syringe Filter, GHP, 13 mm, 0.2 µm, Aqueous,
In rare cases, a solvent might partly or fully dissolve the membrane, resulting in breakthrough and potential contamination of the sample. Aqueous samples are unlikely to damage most membrane materials, particularly hydrophilic. However, pH is a significant factor in determining membrane compatibility.
However we are excited to announce the launch of the NEW wwPTFE universal membrane as a direct replacement for GHP filtration products. Pall’s next generation of universally chemically compatible membrane, our water wettable polytetrafluoroethylene (wwPTFE) membrane, yielded significant performance advantages compared to GHP when extractables, binding, column life and chemical compatibility were evaluated.
Acrodisc® Syringe Filter with wwPTFE membrane & wwPTFE Membrane Disc Filters, Pall. The “universal” membrane filter for all of your analytical filtration requirements. Avoid the expense and inconvenience of keeping a variety of filters on hand. Versatile filter for aqueous and aggressive organic solvent-based solutions.
1) Syringe filter housings are manufactured from solvent-resistant, low-extractable polypropylene resins specifically selected for wide compatibility with common HPLC sample matrices. 2) Solutions at temperatures up to 100°C can be filtered using syringe filters. 3) Syringe filters can be sterilized by autoclave at 125°C for 15 minutes.